Mahnoor Zulfiqar is a doctoral researcher at the Friedrich Schiller University Jena under the supervision of Prof. Dr. Christoph Steinbeck. She joined the group in September 2019.
Mahnoor did her Bachelors (2012-2016) in Biochemistry and Molecular Biology from University of Gujrat, Pakistan. After her BS Graduation, she opted for Masters (2017-2019) in Bioinformatics from COMSATS University Islamabad (CUI), Islamabad, Pakistan.
Her Masters thesis comprised of a comprehensive work on the Drug Discovery for Cardiovascular Diseases particularly targeting Phosphodiesterase Type 5 Enzyme and how to overcome the side effects of 1st generation PDE5 Inhibitors. In this study she performed pharmacophore modeling to filter out the class of natural compounds that have the potential to specifically bind to PDE5 only, rather than other sub-classes of PDEs which produce side effects. With High Throughput Structure based Ligand Screening, final Natural Products were recorded as the lead compounds with least side effects.
With the completion of her Masters degree, she is now working as a doctoral researcher for the research cluster Balance of the Microverse by Jena School of Microbial Communication (JSMC), Friedrich Schiller University Jena. Her PhD project aims at the integrative analysis of Metabolomic and Transcriptomic data generated by Microbial Consortia.